Eli Stone  (Tuesdays, 10:00-11:00 p.m., ET)

With a newfound resolve and sense of his life's purpose -- even if that means being a prophet -- Eli Stone (Jonny Lee Miller, "Trainspotting") ended the show's freshman season by making peace with the Almighty... by having his brain aneurysm -- and the source of his fantastic visions -- removed. He appointed his brother, Nathan (Matt Letscher, "The New Adventures of Old Christine"), his proxy in case the surgery left him in a vegetative state -- which it did. With Eli in a coma and Nathan wrestling with the decision of whether to take his brother off life support, Eli's spiritual guru, Dr. Chen (James Saito, "I Think I Love My Wife"), appealed to Nathan to give Eli more time. And with that reprieve granted, Eli was able to make peace with God -- through a George Michael musical number, of course -- and awake from his coma.

But will Eli's visions cease now that he is free of his aneurysm? Or will they establish once and for all that he is a modern day prophet? The show's second season answers these questions in ways that will surprise viewers and will reaffirm how the show's fresh and accessible approach to issues of faith and spirituality.

"Eli Stone" stars Jonny Lee Miller as Eli Stone, Victor Garber as Jordan Wethersby, Natasha Henstridge as Taylor Wethersby, Loretta Devine as Patti, Sam Jaeger as Matt Dowd, James Saito as Dr. Chen, Matt Letscher as Nathan Stone, Julie Gonzalo as Maggie Dekker and Jason George as Keith Bennett.

Greg Berlanti ("Brothers & Sisters," "Dirty Sexy Money," "Everwood") and Marc Guggenheim ("Brothers & Sisters," "Law & Order," "The Practice") are co-creators and executive producers. David Petrarca ("Everwood," "Big Love") also serves as executive producer and director. The series is produced by ABC Studios.